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Tohru Yoshimura Selected Research

D-serine dehydratase

9/2014Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate.
2/2012Role of zinc ion for catalytic activity in d-serine dehydratase from Saccharomyces cerevisiae.

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Tohru Yoshimura Research Topics

Disease

7Dehydration (Water Stress)
06/2022 - 09/2009
2Nervous System Diseases (Neurological Disorders)
12/2015 - 07/2008
2Hepatocellular Carcinoma (Hepatoma)
08/2003 - 08/2002
1Protein Deficiency
01/2022
1Epilepsy (Aura)
01/2019
1Scrapie
01/2018
1Pheochromocytoma
12/2016
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
07/2008
1Schizophrenia (Dementia Praecox)
07/2008
1Alzheimer Disease (Alzheimer's Disease)
07/2008

Drug/Important Bio-Agent (IBA)

8Serine (L-Serine)FDA Link
06/2022 - 07/2008
6EnzymesIBA
01/2020 - 09/2009
4PyridoxalIBA
01/2022 - 02/2012
2Adenosine Triphosphate (ATP)IBA
06/2022 - 01/2018
2AmmoniaIBA
01/2020 - 09/2014
2serine racemaseIBA
01/2020 - 03/2013
2Pyruvic Acid (Pyruvate)IBA
01/2020 - 09/2014
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
12/2015 - 07/2008
2D-serine dehydrataseIBA
09/2014 - 02/2012
2IntegrinsIBA
08/2003 - 08/2002
1LigandsIBA
06/2022
1Pyridoxine (Pyridoxin)FDA LinkGeneric
01/2022
1SolventsIBA
01/2020
1IsotopesIBA
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2019
1VitaminsIBA
01/2019
1Aconitate Hydratase (Aconitase)IBA
10/2018
1phosphomevalonic acidIBA
10/2018
1Amino AcidsFDA Link
01/2018
1Racemases and Epimerases (Epimerases and Racemases)IBA
12/2016
1HydrogenIBA
03/2013
1Threonine (L-Threonine)FDA Link
02/2012
1Alanine (L-Alanine)FDA Link
02/2012
1Hydroxyl RadicalIBA
02/2012
1S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA
08/2003
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
08/2003
1Cell Surface ReceptorsIBA
08/2003
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
08/2003
1Indicators and Reagents (Reagents)IBA
08/2002
1Mitogen-Activated Protein KinasesIBA
08/2002
1Phosphotransferases (Kinase)IBA
08/2002

Therapy/Procedure

1Drug Therapy (Chemotherapy)
08/2002